The University of Iowa
Department of Pharmacology, Carver College of Medicine
2-252 BSB, 51 Newton Road
Iowa City, IA, 52242

A NIH-funded postdoctoral position is available immediately to study the regulation of expression, trafficking, localization and functions of voltage-gated Na+ and ligand-gated TRP channels by diverse cellular signal transduction pathways that are initiated by factors released from tumor/microenvironment. The laboratory's research is geared towards thorough understanding of tumor-nerve crosstalk via neuronal ion channel modulations that underlie cellular plasticity and regulation of electrical excitability of neurons, in relation to cancer-induced pain and tumor-induced seizure conditions. The laboratory utilizes multidisciplinary approach, which include primary neuronal cultures/co-cultures, biochemical, cell/molecular biological, immunohistochemical and electrophysiological techniques, as well as diverse rodent behavioral assessments. The laboratory has its own tissue culture, biochemical, cell/molecular biological, electrophysiological, microscopy and rodent behavioral analysis facilities. In addition, the University of Iowa Carver College of Medicine has outstanding core research (microscopy & imaging, histopathological, genomic, proteomic and transgenic) facilities, for the rapid advancement of research work.

Qualification

Applicant must be highly motivated individual possessing a PhD or MD/PhD degree with training/experience in patch-clamp electrophysiology (preferably on Nav and/or TRP channels), as well as have very good knowledge in basic cell physiology, as evidenced from peer-reviewed research publications. Experience in intracellular or field potential recordings in brain/spinal cord slices, and any of the above-mentioned techniques will be an added advantage. Graduate students close to completing their doctoral degree in next couple of months are strongly encouraged to apply.

How to Apply

NIH scale (Annual - $38,496 + health care benefits)
Visit: http://www.nature.com/naturejobs/science/jobs/209484-Postdoctoral-Researcher

An opening is now available at Northwestern University for a postdoctoral fellowship in nanotechnology under the joint mentorship of Dr. Chad Mirkin and Dr. Amy Paller.  The focus of this fellowship experience is the use of nanoparticles for delivery of oligonucleotides through skin. The laboratory uses novel polyvalent technology to deliver siRNA and antisense DNA through the epidermal barrier to reach epidermal and dermal targets. 

Current projects target genetic alterations involved in melanoma, carcinoma, inflammatory skin disease, and diabetic wounds. The fellow would be immersed in the activities of the NIH-funded Northwestern Skin Disease Research Center and the International Institute for Nanotechnology.  Applicants must have previous laboratory experience, such as a recent Ph.D. or equivalent degree in the biological sciences; physicians with a research background will also be considered.  Candidates should be highly motivated and a good team players, have excellent communications skills and, ideally, desire a career in cutaneous biology research.

Applicants should submit a cover letter that explains their background and goals, a curriculum vitae, and at least 3 references to Dr. Amy Paller (apaller(at)northwestern.edu).

Contact:

Amy S. Paller, M.D.
Walter J. Hamlin Professor and Chair
Department of Dermatology
Director, Skin Disease Research Center
Northwestern University Feinberg Medical School
676 N. St. Clair, Suite 1600
Chicago, IL 60611-2997

Phone: 312-695-3721 (assistant, Nilda Reyes)
Fax: 312-695-0664

Email: apaller(at)northwestern.edu

Incoming search terms:

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These new buildings create an interconnected McGill University Life Sciences Complex that houses a dynamic research community of over 200 biomedical researchers. In addition to spectacular excellent laboratory space, this new infrastructure includes modern core facilities for FACS, high throughput screening, small molecule and shRNA siRNA screening, imaging, mass spectrometry, 800 & 600 MHz NMR, X-ray crystallography, Biacore T100, deep sequencing, small angle X ray scattering and informatics infrastructure. They also include a new state of the art mouse facility that is equipped for mouse genetics, transgenic animals and for working with BSL-2 and BSL-3 level pathogens.

The goal of these recruitments is to enhance the interdisciplinary research environment areas of Chemical and Structural Biology Program, one of the 5 new research themes of this new research complex. This program explores the underlying biology of human disease by examining the interplay between chemistry, biology and physics. Areas of particular interest include but are not limited to systems biology, structural biology, and bioinformatics.

We invite applications from well-qualified candidates at all stages of their careers who have enthusiasm for multidisciplinary research and are eager to develop novel approaches toward understanding fundamental biological and disease processes. The successful candidate will be provided competitive start up packages and will contribute to the research and teaching missions of one or more of the Departments of the Faculty of Medicine.

Montreal, one of North America’s most culturally diverse and lively cities offers a high quality of life with affordable housing with highly motivated and intelligent students.

Applicants should have a PhD or equivalent and at least three years of postdoctoral research training. Please submit your application electronically at the following website: (http://www.medicine.mcgill.ca/academic/rec_applicationform.htm). In order to complete the application process, please also send to acadpersonnel.med(at)mcgill.ca a single PDF file that includes a letter outlining your current and future research interests, a copy of your CV and the names and addresses of three references.

Informal inquiries to:
Dr. David Y Thomas
david.thomas(at)mcgill.ca

All qualified applicants are encouraged to apply; however, Canadians and permanent residents will be given priority. McGill University is committed to diversity and equity in employment. It welcomes applications from indigenous peoples, visible minorities, ethnic minorities, persons with disabilities, women, persons of minority sexual orientations and gender identities and others who may contribute to further diversification.

Faculty Positions in Biomedical Research, McGill University
Country: Canada
Application Deadline: 2011-May-24

http://www.career.edu/index.php?post_id=8915

Incoming search terms:

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A postdoc position is available immediately for an NIH-funded project investigating the synaptic mechanisms of coding transformations in auditory cortex using whole-cell recordings and optogenetics in awake rodents. Experience with auditory neurophysiology and/or whole-cell recording methods is a plus.

Application Deadline 2011-May-20

via: http://www.career.edu/index.php?post_id=8872

Degree Required: PhD
Assignment Start Date: 2/1/2010
Estimated End Date: 12/31/2010
FULL TIME Contract Position Medical Benefits-Vacation-Sick Time-401K

Requirements:
In vitro molecular biology skills (cell culture) w/preference kidnecells/kidney background and some in vivo animal research experience (w/preference to rodent/rat/renal function experience) or strong interest and evidence of ability to develop in vivo research experience

In vivo animal physiology, pharmacology or toxicology skills (e.g. design and conduct studies) w/preference renal physiology, pharmacology, toxicology background and metabolism studies and some in vitro molecular biology research experience (w/preference to cell culture, renal cell experience) or strong interest and evidence of ability to develop in vitro research experience. Office (internet, document processing, data handling and presentation preparation) and laboratory computer (data collection, analysis, graphing) required

Responsibilities:
Primary Objective:
MUST DELIVER: In consultation with CLIENT to CPI Preclinical Safety Testing Consortium (PSTC) Nephrology Working Group (NWG) design, agree, conduct, analyze samples and date and report in vivo animal studies to expand and extend understanding, utilization, interpretion, and benefit-risk of new urinary biomarkers to DETECT drug-induced kidney injury (DIKI), starting with those biomarkers previously agreed by FDA valid for use in rats.

Secondary Objective: In consultation with supervisor and collaboration with Client's Renal Safety Science Workijn Group, translate knowledge gained from in vivo urinary biomarker science directed to DETECT DIKI and apply design, develop, conduct, analyse samples and data, and report new in vitro models and higher through-put screening tools useful to PREDICT DIKI potential of new compounds (e.g. prior to in vivo testing).

PLEASE SEND RESUMES TO: christina.thompson@yoh.com

http://www.yoh.com/

Employer: Global Pharmaceutical Company
Recruiter: Yoh Managed Services
Location: Wilmington, DE, United States
Expires: March 08, 2010

Incoming search terms:

• pharmacology scholarship

Postdoctoral positions are open in the Tulane Cancer Center of the Tulane University. Research focuses on the identification and characterization of risk factors for carcinogenesis and cancer progression, with a special focus on prostate cancer. Ongoing projects include the genetic and molecular characterization of genomic instability and tumor heterogeneity of prostate and other types of tumors. The immediate goal is to measure the effect of genomic instability (measured as somatic variation rate) in outcomes research.

Tulane Cancer Center provides an intellectually stimulating environment with opportunities for collaborations and cross-disciplinary training. Candidates must have a Ph.D. and/or MD and a background in genetics or molecular biology. Knowledge of next-generation sequencing is beneficial. Please send CV including bibliography and names of three references to Nick Makridakis, Ph.D., Tulane Cancer Center, Tulane University, New Orleans, LA.

How To apply

Email: nmakrida@tulane.edu

http://www.tulane.edu/

Employer: Tulane Cancer Center/ Nick Makridakis, Tulane University of Louisiana
Location: New Orleans, LA, United States
Expires: February 19, 2010

The Behavioral Health Fellowship has graduated more than 240 fellows over the past twentyseven years. Over 60 of these fellows have been hired by Harvard Vanguard Medical Associates as permanent clinicians, a fact that attests to the high quality of our participants and the excellence of our training. Fellows have gone on to assume leadership positions within HVMA and in the larger community.

Eligibility Requirements and Compensation:
Nurses and Social Workers who have completed their Master’s Degree. Psychologist applicants who have completed requirements for their PhD and a minimum of a one year pre-doctoral internship. Fellows receive $15,000 per year for the half- time fellowship and three weeks vacation/sick time.

Fellowship Application Deadline:7 January 2011
Further Fellowship Information and Application

Our laboratory aims to understand the neural basis of Autism spectrum disorders (ASDs). ASDs are life-long complex neurological disorders that affect multiple aspects of development, learning, and adaptation to community, and thus represent a pressing public health need.

The etiologies of ASDs are poorly understood, but are thought to include both genetic and environmental influences. We employ a variety of genomic and proteomic techniques such as ChIP-seq, RNA-seq, Hi-C, and ChIP-MS/MS with genetically modified mouse models to focus on two frontiers: 1) the molecular and cellular mechanisms underlying the etiology of ASDs; 2) the molecular targets for the medication of ASDs.

Postdoctoral positions are currently available for at least three years. Fellows will have an opportunity to work in a highly interactive multidisciplinary research environment at the University of Pennsylvania with cutting-edge genomic tools. Individuals with a background in computational biology and experience in neuroscience are encouraged to apply. Applicants should please submit a CV and contact information for three references to Dr. Zhaolan (Joe) Zhou. (zhaolan at mail.med.upenn.edu).

Application Deadline 31-Dec-10

Please send CV, brief statement of research interests and names of three references to:

Dr. Pao-Tien Chuang Cardiovascular Research Institute University of California, San Francisco Genentech Hall, Room S472B 600 16th Street San Francisco, CA 94158

E-mail: pao-tien.chuang@ucsf.edu

The University of California is an equal opportunity employer

Post-doctoral position available to study the molecular mechanisms of cell-cell interactions in mammalian development and disease, using mouse as a model system. We focus on the Hedgehog (Hh) signaling pathway which is critical for many aspects of embryonic development, and aberrant regulation of the pathway results in a wide variety of congenital defects and cancers.

The two main areas of research interest are: (1) The molecular characterization of the Hedgehog signaling pathway. We wish to understand how the lipidated Hh ligand generates a morphogen gradient and how the Hh signal is transduced in Hh-responsive cells; (2) The roles of Hedgehog signaling in postnatal physiology and homeostasis such as stem cell maintenance and cancer formation. We investigate regulation of neural and pulmonary stem cells by Hh signaling and how aberrant Hh signaling leads to brain tumors and lung cancers. In all of our studies, a combination of mouse genetics (transgenic and knockout mice), cell biology and biochemistry are employed.

Please visit our webpage at http://www.cvri.ucsf.edu/~chuang/links.html or http://www.ucsf.edu/bms/faculty/chuang.html for more information.

Please send CV, brief statement of research interests and names of three references to:

Dr. Pao-Tien Chuang Cardiovascular Research Institute University of California, San Francisco Genentech Hall, Room S472B 600 16th Street San Francisco, CA 94158

E-mail: pao-tien.chuang@ucsf.edu

The University of California is an equal opportunity employer

Expires: October 04, 2010